Curious about Phenibut?
Do you wonder about the benefits of Phenibut for regulating mood and anxiety?
Then you’ve come to the right place! Whether you’re considering using Phenibut for anxiety relief or simply want to learn more about this popular nootropic, we’ve got you covered.
In this comprehensive review, we will cover everything you MUST know about Phenibut, including its uses, dosage recommendations, and potential side effects. We also dive into the science behind Phenibut, how it works in the body, and the most effective ways to use it.
We even answer your most important questions, including:
By the end of this review, you’ll have all the information you need to make an informed decision on Phenibut and its powerful nootropic.
So, let’s get started!
P.S: Order Phenibut here from a world-class vendor!
(Phenibut.com, sponsored) Phenibut is one of the most popular and powerful nootropics available today.
What is Phenibut?
Phenibut is one of the most popular and powerful nootropics available today.
Phenibut was first researched and developed in the Soviet Union in the 1960s. It was originally studied for its anxiolytic and antidepressant effects in humans, but it has since been used for a variety of purposes, including:
Phenibut is best known for its anxiolytic and cognitive-enhancing effects, including its ability to boost GABA and dopamine levels in the brain.
Research shows dopamine and GABA are powerful neurotransmitters which decrease anxiety and improve overall mood in humans, which explains Phenibuts powerful benefits [4]!
So how does Phenibut work?
Phenibut is technically a GABA-B agonist. This means it selectively binds to and activates GABA-B receptors in the brain [5]. The latest studies show GABA is an inhibitory neurotransmitter which promotes relaxation and a sense of calm in users [6].
Research also shows that Phenibut can boost overall brain dopamine levels, a powerful neurotransmitter which elevates mood, focus, and concentration.
It’s rare to come across a nootropic that boosts both dopamine and GABA simultaneously, which explains the large amount of interest in Phenibut amongst researchers.
Understanding the Mechanism of Action of Phenibut
Phenibut is able to exert its powerful effects as a nootropic by increasing dopamine and GABA levels in the brain.
From there, these powerful neurotransmitters provide numerous physiological benefits including decreased perception of stress, improved focus and cognitive performance, and more.
Here’s a closer look at how Phenibut is able to achieve these outcomes:
Overall, Phenibut’s unique ability to boost both GABA and Dopamine neurotransmitters in the brain is responsible for its powerful cognitive-enhancing and mood-elevating effects.
Phenibut Benefits
Phenibut has been successfully studied since the 1960s in the former Soviet Union, and researchers are consistently amazed at its wide range of benefits.
It has the unique ability to boost GABA and dopamine levels in the brain, meaning it has numerous benefits and use-cases.
Some of its most powerful benefits include:
Phenibut clearly has many powerful benefits for users and research subjects. However, it’s important to be aware of its potential side effects as well before studying its unique nootropic properties.
Phenibut Side Effects
Phenibut has earned a reputation as one of the safest nootropics available – provided you are taking the recommended dosage of 250 – 1,500 mg per day.
While side effects are relatively rare, there are some that you should be aware of. Some of the most common side effects of Phenibut include:
While these side effects are possible, they are relatively rare.
The easiest way to avoid these potential side effects is to start with a small dose of Phenibut, and gradually increase the dose until you find your “sweet spot.”
Phenibut Withdrawal Symptoms
Phenibut is generally considered one of the safest nootropics available today. However, when used at high doses for extended periods of time, some users may be at risk for developing withdrawal symptoms.
Abruptly stopping Phenibut use may result in the following withdrawal symptoms in some individuals:
Withdrawal symptoms from Phenibut use varies depending on multiple factors, including genetic predisposition, dosages used, and duration of use.
Fortunately, Phenibut withdrawal symptoms can be minimized or avoided entirely by using low-moderate doses, and cycling off Phenibut for a period of time to re-sensitize your body to its effects.
When using Phenibut with high doses for extended periods of time, it is essential to gradually reduce your dosage to minimize the risk of experiencing withdrawal symptoms.
(Phenibut.com, sponsored) When using Phenibut with high doses for extended periods of time, it is essential to gradually reduce your dosage to minimize the risk of experiencing withdrawal symptoms.
Phenibut Dosage Calculator and Chart
By now you’re probably curious about how much Phenibut to use… The truth is the optimal Phenibut dose depends on numerous factors, including individual response to the nootropic, bodyweight, age, and other factors.
However, it is possible to make some general guidelines for optimal dosing protocols:
Phenibut Dosage Calculator
It is also possible to calculate your optimal Phenibut dosage based on your bodyweight. Researchers have found the following dosage calculator to be particularly helpful for this purpose:
For example, here are some sample calculations for individuals with different body weights:
We recommend starting with a relatively low dose, and slowly increasing until you find your sweet spot.
It’s important to note that this dosage calculator is just a rough starting point. Individual responses to Phenibut vary widely, so the optimal dose for one person may be significantly higher or lower than that for another.
Phenibut Dosage Recommendations
Here are some general guidelines for optimal Phenibut dosages:
It is essential to start with a low dose and gradually increase the dosage as needed. Phenibut should not be taken for more than two weeks continuously.
It is also important to cycle dosage to prevent tolerance and dependence.
Phenibut Review | Does the Nootropic Actually Work?
Research shows that Phenibut is a powerful Nootropic with numerous benefits for improving mood, memory, concentration, and overall cognitive performance. But does it actually work in the real world?
In other words, are users’ real-world experience backing up what researchers are finding in the lab?
The short answer is a YES – Phenibut works extremely well, and is one of the strongest overall nootropics. Let’s take a closer look at our own experience from testing the nootropic, as well as case studies from other individuals.
Our Experience With Phenibut…
We have been using Phenibut for several years, and we must say it is one of our absolute favorite nootropics.
We don’t like to use it all the time, as there is a real risk for developing dependence or withdrawal symptoms. However, when used in moderation Phenibut is an absolute game-changer.
Here are a few of the benefits we personally experienced while using Phenibut:
We even noticed other benefits like improved quality and quantity of sleep. Some of our testers experienced jitters while using higher doses, but this was resolved by just adjusting the dose.
Phenibut User Reviews…
Based on the feedback of thousands of real-world Phenibut users, it’s safe to say that other individuals are experiencing many of the same mood-enhancing and cognitive-boosting benefits that we have experienced.
For example, here is one recent review from a verified Phenibut user:
“Have been taking Phenibut for 4 years now. Works great with no side effects. Calms my anxiety, improves my sleep, and provides me with motivation and an out-going personality. Must be taken in small doses (1,000mg or less a day) and never taken more than 2-3 days in a row. I actually take every other day and I would not call it addictive at all.” - Rick B
This kind of feedback is incredibly common from first-time Phenibut users. They are simply blown away by how powerful it is!
Overall, Phenibut works just as well in the real world as it does in research studies. If you are looking for a powerful nootropic with numerous benefits and few side effects, then Phenibut is an excellent choice!
Forms of Phenibut
Before purchasing Phenibut from a high-quality online vendor like Science.bio, it’s important to learn about the different types of Phenibut that are available.
The truth is Phenibut comes in several different forms, including capsules, liquids, powder, and crystals. There are also several different types of Phenibut, including Phenibut HCL and Phenibut FAA.
Let’s start by examining the different types of Phenibut, followed by the different administration forms.
Phenibut Types
There are three main types of Phenibut: Phenibut HCL, Phenibut FAA, and F-Phenibut.
They all have similar properties, but vary significantly in terms of their potency, speed of absorption, and duration of effects.
Overall, we recommend beginners start with Phenibut HCL. More experienced users can use a more powerful version like F-Phenibut to get maximum results.
Phenibut Forms
Phenibut comes in several different administration forms, each with their own unique advantages and disadvantages.
These forms include:
To summarize, Phenibut can be administered in different forms, including capsules, liquid, powder, and crystals. Each form has its advantages and disadvantages.
There are also different types of Phenibut including Phenibut HCL or Phenibut FAA which have slightly different effects in the body.
Users are encouraged to research each form and type of Phenibut to better understand their advantages and disadvantages.
Where To Buy Phenibut Online?
Purchasing from a high-quality online Phenibut vendor is absolutely critical.
After all, there is nothing worse than realizing you tested a low-quality product that is filled with cheap fillers and impurities…
Our team of experts has personally tested and reviewed every major online Phenibut vendor. We believe the best vendor depends on what type of Phenibut you are looking to purchase.
Here are our top recommendations:
Science.bio is our #1 overall choice, but researchers looking to study the effects of Phenibut capsules or fine crystals may prefer ordering from Liftmode or Pure Rawz.
Here is some additional information on each vendor to help you make an informed decision:
1. Science.bio
Science.bio is the #1 online Phenibut vendor for researchers looking to study the effects and benefits of this powerful nootropic product.
The thing that separates Science.bio from other Phenibut vendors is their commitment to quality. They test all of their products using rigorous 3rd-party testing protocols, which ensures you get the highest quality product.
Other benefits of Science.bio include:
Overall, Science.bio is the clear #1 choice for anyone looking for a high quality online Phenibut vendor. This is especially true if you are interested in Phenibut liquids or powders.
But don’t just take our word for it - here is what real Science.bio customers are saying about this product:
“Highly recommended for reliable research products and exceptionally helpful & prompt customer service. I have been purchasing from Science.bio starting in early August 2020, and I have been satisfied with multiple orders each month since. Consistent quality with a wide variety of safe and secure payment methods to work with!” - VW
With reviews like these, its easy to see why Science.bio is one of the most reputable online Phenibut vendors in the world!
2. Liftmode
Liftmode is one of the premier online Phenibut vendors that offers unmatched quality for Phenibut liquids and powders.
Liftmode specializes in producing high-quality nootropics supplements - including Phenibut.
Here are just a few of the reasons they are one of our preferred vendors:
Overall, Liftmode is an excellent choice for anyone interested in testing out the powerful effects of Phenibut.
3. Pure Rawz
Pure Rawz is a vendor that specializes in producing premium quality Phenibut powders and fine crystals. They also offer a wide variety of nootropics and other research chemicals, regardless of your individual goals.
One of the things that separates Pure Rawz from other online Phenibut vendors is their commitment to manufacturing the highest quality products.
All of their Phenibut products undergo strict third-party lab testing to ensure purity and potency of their products. They also offer incredibly fast shipping times, competitive pricing, and multiple payment options including credit card, paypal, bitcoin, and Zelle.
(Phenibut.com, sponsored) Phenibut and F-Phenibut are two closely related compounds that have similar, but slightly different effects in the body.
Phenibut vs. F-Phenibut
Phenibut and F-Phenibut are two closely related compounds that have similar, but slightly different effects in the body.
Both of these nootropics help to relieve symptoms of anxiety and improve overall mood. However, there are some key differences in terms of their potency, and how long they remain active in the body.
Here are some of the key differences between Phenibut and F-Phenibut:
To summarize, Phenibut HCL and F-Phenibut are two popular forms of the powerful nootropic Phenibut.
While they have similar overall effects in the body, they differ significantly in terms of their potency, speed of absorption, and half-life in the body.
Is Phenibut Legal?
You may be wondering if Phenibut is actually legal. The truth is the legal status of Phenibut varies from one country to the next.
While some countries like the United States make it legal for individuals to purchase Phenibut without a valid doctor’s prescription, other countries have more restrictive laws governing its use and possession.
Here’s a breakdown of the legal status of Phenibut in several Western countries:
Phenibut is definitely one of those “grey-area” nootropics where it is legal in some countries, and illegal in others.
If you are interested in purchasing and using Phenibut, we recommend verifying the legal status of the nootropic in your country.
Is Phenibut Safe?
Phenibut is generally considered a safe nootropic – especially when taken at the recommended dosages. However, like any supplement or medication, Phenibut can cause side effects when used improperly or at excessively high doses.
Here are some key points to consider when evaluating the safety of Phenibut:
Overall, Phenibut is a very safe nootropic when used correctly.
However, users are encouraged to monitor for side effects and adjust their dosage as necessary to minimize their occurrence.
Phenibut | Review of Uses, Dosage, and Side Effects
Phenibut is a powerful nootropic known for its anxiolytic effects and potential cognitive-enhancing benefits.
Phenibut is generally considered safe when used as directed, but it helps to monitor for side effects – especially if you are new to the nootropic.
They manufacture the highest-quality Phenibut that is rigorously tested for purity and potency, so you know you are getting excellent value for your money.
Always remember to use Phenibut responsibly. When in doubt, start with a relatively low dose to gauge your individual response, and slowly adjust upwards from there.
References
- Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81. doi: 10.1111/j.1527-3458.2001.tb00211.x. PMID: 11830761; PMCID: PMC6494145.
- Malík M, Tlustoš P. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Nutrients. 2022 Aug 17;14(16):3367. doi: 10.3390/nu14163367. PMID: 36014874; PMCID: PMC9415189.
- Sejbuk M, Mirończuk-Chodakowska I, Witkowska AM. Sleep Quality: A Narrative Review on Nutrition, Stimulants, and Physical Activity as Important Factors. Nutrients. 2022 May 2;14(9):1912. doi: 10.3390/nu14091912. PMID: 35565879; PMCID: PMC9103473.
- Nuss P. Anxiety disorders and GABA neurotransmission: a disturbance of modulation. Neuropsychiatr Dis Treat. 2015 Jan 17;11:165-75. doi: 10.2147/NDT.S58841. PMID: 25653526; PMCID: PMC4303399.
- Evenseth LSM, Gabrielsen M, Sylte I. The GABAB Receptor-Structure, Ligand Binding and Drug Development. Molecules. 2020 Jul 7;25(13):3093. doi: 10.3390/molecules25133093. PMID: 32646032; PMCID: PMC7411975.
- Hyland NP, Cryan JF. A Gut Feeling about GABA: Focus on GABA(B) Receptors. Front Pharmacol. 2010 Oct 4;1:124. doi: 10.3389/fphar.2010.00124. PMID: 21833169; PMCID: PMC3153004.
- Brown KM, Roy KK, Hockerman GH, Doerksen RJ, Colby DA. Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators. J Med Chem. 2015 Aug 27;58(16):6336-47. doi: 10.1021/jm5018913. Epub 2015 Apr 24. PMID: 25856547; PMCID: PMC7485174.
- Shaye H, Stauch B, Gati C, Cherezov V. Molecular mechanisms of metabotropic GABAB receptor function. Sci Adv. 2021 May 28;7(22):eabg3362. doi: 10.1126/sciadv.abg3362. PMID: 34049877; PMCID: PMC8163086.
- Komissarov IV, Abramets II. Ionnye mekhanizmy éffektov fenibuta i GAMK, ne sviazannykh s izmeneniem funktsii khlornykh kanalov [Ionic mechanisms of the effects of phenibut and GABA unrelated to changes in the function of chloride channels]. Neirofiziologiia. 1985;17(4):481-9. Russian. PMID: 2995847.
- Althobaiti YS, Almutairi FM, Alshehri FS, Altowairqi E, Marghalani AM, Alghorabi AA, Alsanie WF, Gaber A, Alsaab HO, Almalki AH, Hakami AY, Alkhalifa T, Almalki AD, Hardy AMG, Shah ZA. Involvement of the dopaminergic system in the reward-related behavior of pregabalin. Sci Rep. 2021 May 19;11(1):10577. doi: 10.1038/s41598-021-88429-8. PMID: 34011976; PMCID: PMC8134490.
- Zheng KH, Khan A, Espiridion ED. Phenibut Addiction in a Patient with Substance Use Disorder. Cureus. 2019 Jul 24;11(7):e5230. doi: 10.7759/cureus.5230. PMID: 31565631; PMCID: PMC6758981.
- Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81. doi: 10.1111/j.1527-3458.2001.tb00211.x. PMID: 11830761; PMCID: PMC6494145.
- Zheng KH, Khan A, Espiridion ED. Phenibut Addiction in a Patient with Substance Use Disorder. Cureus. 2019 Jul 24;11(7):e5230. doi: 10.7759/cureus.5230. PMID: 31565631; PMCID: PMC6758981.
- Shul’gina GI, Ziablitseva EA. Vliianie proizvodnogo GAMK fenibuta na obuchenie [Effect of the GABA derivative phenibut on learning]. Vestn Ross Akad Med Nauk. 2005;(2):35-40. Russian. PMID: 15776965.
- Zvejniece L, Vavers E, Svalbe B, Veinberg G, Rizhanova K, Liepins V, Kalvinsh I, Dambrova M. R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects. Pharmacol Biochem Behav. 2015 Oct;137:23-9. doi: 10.1016/j.pbb.2015.07.014. Epub 2015 Jul 31. PMID: 26234470.