Looking for an in-depth adrafinil review?
Well, it’s time to stop looking, because you’ve found it!
This is a helpful guide to using and purchasing adrafinil, a research chemical that’s actually a metabolic prodrug of modafinil (which means that it’s converted to modafinil after ingestion).
Adrafinil is interesting because in the US it’s neither a supplement nor a drug. In most countries it’s treated as a research chemical, meaning you don’t need a prescription to purchase it. However, it’s only available for research purposes.
In this article we’re gonna deep dive into what it is, how it works, IF it works, its potential benefits and effects, the right dosage (including a little info about stacking it with other nootropics) and the best place to buy it online.
We even answer your most important questions, including:
All of this stuff is super important to know if you’re planning on purchasing it.
Ready to learn more about adrafinil? Then read on!
P.S: Click here to order Adrafinil from the best vendor in the world!
(Adrafinil.com, sponsored) Adrafinil is a research chemical that’s nearly identical to modafinil in terms of its structure.
Understanding the Mechanism of Action of Adrafinil
Adrafinil is a research chemical that’s nearly identical to modafinil in terms of its structure. In fact, it’s a prodrug of modafinil, meaning that your body metabolizes it into modafinil after ingestion.
Therefore, it potentially provides some of the same benefits and effects. Adrafinil’s original and primary use was as a eugeroic (wakefulness agent) for people with sleep disorders [1, 2].
Adrafinil was actually discovered before modafinil was, and beat modafinil to the prescription drug market by a few years as a prescription wakefulness agent in France. However, pharmaceutical companies quickly lost interest in adrafinil after the more powerful modafinil came on the scene.
Olmifon, the name brand of adrafinil, was manufactured until 2011, when it was discontinued.
However, adrafinil is still produced by other companies, and remains available for purchase in several countries where it was never classified as a prescription drug, including the United States.
Nootropics researchers are particularly interested in its nootropic, or brain-enhancing, benefits. Adrafinil may in fact provide some powerful cognition-boosting effects.
Adrafinil Benefits
Here are the top five nootropic benefits of adrafinil. It’s important to note that these benefits have mostly been seen in animal studies, as the available research on the effects of adrafinil in humans is very limited.
1. Alertness
Adrafinil is a wakefulness agent by design, and was originally developed as a prescription drug for people with sleep disorders. It may help you to stay more alert during the day [1].
Several animal studies have noted increases in alertness and activity after adrafinil administration, as well [3, 4, 5].
2. Energy
On a similar note, adrafinil may provide a more sustained level of energy throughout the day to help prevent fatigue or slumps.
Increased energy was its original purpose when it was marketed as a prescription drug in France, and many researchers have likewise reported that it increases energy levels [1].
3. Productivity
In several animal studies in aged beagles, mice, and rhesus monkeys, researchers have noted that adrafinil led to increases in locomotion, or movement and activity [3, 4, 5, 6].
Although results are mixed, most studies note this effect [7].
In humans, this could potentially translate to an increase in productivity. However, more research in humans is needed.
4. Performance
One small study in aged beagles investigated the effects of adrafinil on test performance [8].
Researchers found that adrafinil significantly improved their performance, reducing errors and the time it took the dogs to complete the task [8].
This data is derived from early animal research, but nonetheless it’s promising research and provides some insight into how adrafinil may affect human subjects.
5. Learning
The same beagle study noted improvements in learning and information processing, which resulted in the dogs’ improved performance [8].
Given its potential to cause improvements in learning, memory, test-taking, and cognitive performance, adrafinil is a solid starting point for researchers interested in nootropics.
Adrafinil Side Effects
Adrafinil is generally considered to be a safe nootropic compound – especially when using the recommended dosages. However, like any supplement or medication, there are potential side effects that future Adrafinil users MUST be aware of.
Some of the most common side effects associated with Adrafinil use include:
It is important to monitor for these side effects when using Adrafinil and to discontinue use if any negative symptoms occur.
Fortunately, these side effects are rare, and most responsible Adrafinil users never experience them while using the nootropic.
Adrafinil Dosage Calculator and Chart
Anyone interested in using Adrafinil should familiarize themselves with the recommended dosage guidelines.
Here is a dosing calculator and chart to help you determine the appropriate Adrafinil dosage based on your weight and desired effects:
Dosing Calculator
To calculate your Adrafinil dosage, use the following formula:
For example, here are some sample calculations for individuals with different body weights:
For example, a person weighing 200 pounds would take anywhere from 200 - 600 mg of Adrafinil as their starting dose.
Dosing Chart
Truth be told, using an Adrafinil dosing chart can be a little bit confusing. Here are some general guidelines for low / medium / high Adrafinil doses:
It’s important to note that higher doses of Adrafinil can increase the risk of negative side effects such as headaches, nausea, and liver toxicity.
It is recommended to start with a low dose and gradually increase as needed while monitoring for any negative symptoms.
(Adrafinil.com, sponsored) Adrafinil is a popular nootropic compound that is known for its ability to enhance cognitive function and promote wakefulness.
Adrafinil Review | Does the Nootropic Actually Work?
Adrafinil is a popular nootropic compound that is known for its ability to enhance cognitive function and promote wakefulness.
But does it actually work? Here’s what you need to know…
Our Experience:
We have been using and testing Adrafinil for years, and we can confirm its powerful benefits for improved mood, focus, concentration, and overall cognitive performance.
We felt more productive while taking Adrafinil and able to tackle tasks with greater ease. Adrafinil sometimes feels like a real “Limitless Drug,” where you are in the zone and operating at your maximum potential.
We also experienced virtually zero side effects while using Adrafinil. Other benefits that we experienced included:
Adrafinil works so well for us, that we continue to use it whenever we are busting out a long work day and need to perform at our absolute best.
User Reviews:
A quick search online reveals thousands of high-performing individuals who are getting incredible results from Adrafinil. Most users are raving about they feel while using Adrafinil – especially while performing difficult work tasks.
Here is what one new Adrafinil user had to say about the product:
“Adrafinil is a game-changer for me. I used to struggle with fatigue and brain fog all the time, but since I started taking Adrafinil, I have so much more energy and mental clarity. It’s not a magic pill – I still have to put in the work – but it definitely helps me stay focused and productive. I’m so glad I discovered this product!” - Robert N.
Overall, most users are blown away by the effects of Adrafinil. As long as you take it first thing in the morning, you can expect all-day energy and unbelievable cognitive performance.
Forms of Adrafinil
Adrafinil is available in a few different forms, each with its own advantages and disadvantages. Here are the most common forms of Adrafinil:
Overall, Adrafinil capsules are the most popular form and ideal for new Adrafinil users. However, Adrafinil powders and liquids are also viable options as well.
Where To Buy Adrafinil Online?
By now you’re probably wondering where to purchase high-quality Adrafinil online. Our team of experts has personally tested every major online Adrafinil vendor.
After extensive testing, we finally settled on three major options:
Science.bio is our favorite overall vendor. They produce superior quality Adrafinil liquid and powders. However, we recommend Pure Rawz for the highest quality Adrafinil capsules.
1. Science.bio
Science.bio is a well-known vendor of Adrafinil powder and other nootropic supplements. They pride themselves on providing high-quality products that are rigorously tested for purity and potency.
Here are some benefits of purchasing Adrafinil through Science.bio:
Overall, Science.bio is the clear #1 choice for anyone looking for a high-quality online Adrafinil vendor.
If you’re ready to place your first order with Science.bio, here is where you can learn more.
2. Pure Rawz
Pure Rawz is another extremely high quality online Adrafinil vendor. They offer a wide variety of products, including nootropics and other research chemicals.
Just like Science.bio, they pride themselves in manufacturing some of the highest quality products that money can buy.
They are also our #1 recommendation for anyone looking to purchase Adrafinil capsules online.
Benefits of Pure Rawz include:
In summary, Pure Rawz is another excellent option for those looking for affordable Adrafinil capsules and other products.
Here is where you can learn more.
(Adrafinil.com, sponsored) In summary, Pure Rawz is another excellent option for those looking for affordable Adrafinil capsules and other products.
Adrafinil vs. Modafinil
Adrafinil and Modafinil are two popular nootropic compounds that are known for their ability to enhance cognitive function and promote wakefulness.
Here are some of the key differences between Adrafinil and Modafinil:
Overall, Adrafinil and Modafinil have many similarities, but they also have distinct differences that potential users must be aware of.
Perhaps most importantly, Adrafinil is legal to purchase in the US and other countries without a prescription, while Modafinil often requires a legit doctor’s prescription.
Adrafinil vs. Fladrafinil
Adrafinil and Fladrafinil are two popular nootropic compounds that are often compared due to their similar effects. Here’s a closer look at the differences between Adrafinil and Fladrafinil:
Adrafinil
Adrafinil is a prodrug of Modafinil, meaning that it is metabolized in the body to produce Modafinil. It is known for its wakefulness-promoting effects and is often used as a cognitive enhancer. Here are some key differences and benefits of Adrafinil:
Fladrafinil
Fladrafinil is a derivative of Adrafinil and has been shown to be more potent and have a quicker onset of action. Here are some key differences and benefits of Fladrafinil:
Adrafinil and Fladrafinil are both powerful nootropic compounds that can be used to promote wakefulness and cognitive function.
Adrafinil is less potent and takes longer to take effect, but may be a safer option for those concerned about liver health. Fladrafinil is more potent and has a quicker onset of action, but may carry a higher risk of side effects.
Adrafinil vs. Hydrafinil
Adrafinil and Hydrafinil are two wakefulness-promoting drugs that have some similarities, but also have key differences.
Here are some of the differences between the two:
Overall, both Adrafinil and Hydrafinil are wakefulness-promoting drugs that can improve cognitive function and promote alertness.
However, Adrafinil is generally considered to be a better overall choice for most users.
Adrafinil Stacks | What Combinations Work?
Adrafinil is often used in combination with other supplements for even greater benefits for mood and cognitive performance.
Here are some of the most popular Adrafinil stacks and the science behind them.
In summary, Adrafinil can be stacked with a variety of supplements and nootropics to enhance its effects and promote cognitive function. Of course, users are encouraged to test Adrafinil on its own before “stacking” it with other compounds.
Is Adrafinil Legal?
Adrafinil is 100% legal to purchase and use in the United States and most western countries. This makes it an excellent alternative to Modafinil and other nootropics, which typically require a doctor’s prescription.
Here is the legal status of Adrafinil in various English-speaking countries:
If you do not live in one of these countries, we encourage you to verify the legal status of Adrafinil for your legal jurisdiction. However, as a general rule of thumb, Adrafinil is generally legal in most countries around the world.
Adrafinil | Review of Uses, Dosage, and Side Effects
Adrafinil is a prodrug of modafinil with a similar chemical structure. Because of this, it may offer some brain-enhancing benefits — like increased focus and concentration, lasting energy and better memory.
However, how it affects the individual depends on their unique body chemistry — some subjects have reported that it worked great for them, while others have reported minimal effects.
If you plan to purchase adrafinil for research, the best place to buy it from is Science.bio because of their strict quality control practices and commitment to great service.
In many countries — the US, the UK and Canada included — adrafinil is not a prescription drug.
We like adrafinil because it provides nootropic benefits, but isn’t a prescription drug and can be ordered online for research purposes.
References
- Ameline A, Gheddar L, Raul JS, Kintz P. Identification of adrafinil and its main metabolite modafinil in human hair. Self-administration study and interpretation of an authentic case. Forensic Sci Res. 2020;5(4):322-326. Published 2020 Jan 29. doi:10.1080/20961790.2019.1704482
- U.S. National Library of Medicine. Modafinil. MedlinePlus website. February 15, 2016. https://medlineplus.gov/druginfo/meds/a602016.html
- Siwak CT, Callahan H, Milgram NW. Adrafinil: effects on behavior and cognition in aged canines. Prog Neuropsychopharmacol Biol Psychiatry. 2000;24(5):709-726. doi:10.1016/s0278-5846(00)00103-2
- Siwak CT, Gruet P, Woehrlé F, Muggenburg BA, Murphey HL, Milgram NW. Comparison of the effects of adrafinil, propentofylline, and nicergoline on behavior in aged dogs. Am J Vet Res. 2000;61(11):1410-1414. doi:10.2460/ajvr.2000.61.1410
- Billiard M, Broughton R. Modafinil: its discovery, the early European and North American experience in the treatment of narcolepsy and idiopathic hypersomnia, and its subsequent use in other medical conditions. Sleep Med. 2018;49:69-72. doi:10.1016/j.sleep.2018.05.027
- Milhaud CL, Klein MJ. Effets de l’adrafinil sur l’activité nocturne du macaque rhésus (Macaca mulatta) [The effect of adrafinil on the nocturnal activity of the rhesus monkey (Macaca mulatta)]. J Pharmacol. 1985;16(4):372-380.
- Siwak CT, Gruet P, Woehrlé F, et al. Behavioral activating effects of adrafinil in aged canines. Pharmacol Biochem Behav. 2000;66(2):293-300. doi:10.1016/s0091-3057(00)00188-x
- Milgram NW, Siwak CT, Gruet P, Atkinson P, Woehrlé F, Callahan H. Oral administration of adrafinil improves discrimination learning in aged beagle dogs. Pharmacol Biochem Behav. 2000;66(2):301-305. doi:10.1016/s0091-3057(00)00175-1
- N = de Belleroche J, Cook GE, Das I, et al. Erythrocyte choline concentrations and cluster headache. Br Med J (Clin Res Ed). 1984;288(6413):268-270. doi:10.1136/bmj.288.6413.268