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Orchard Park, N.Y. • Buffalo Bills running back LeSean McCoy is questionable and will be a game-time decision for Buffalo's upcoming game against the Miami Dolphins.

McCoy returned to practice on a limited basis Friday after sitting out Thursday. He revealed he suffered the injury in Buffalo's Wednesday practice session at the start of individual drills.

"We're confident in the guys that we have behind him but not ruling Shady out at all," Bills head coach Rex Ryan said. "He looked pretty good. So we'll be smart with him, but he looked pretty good."

McCoy has been the driving force behind the Bills offense this year and has gotten off to a hot start. The Bills (4-2) lead the league in rushing and McCoy is second in the NFL with 587 yards, behind only Dallas rookie Ezekiel Elliott.

McCoy said the injury is to his left hamstring, the same hamstring he injured last season. McCoy injured his hamstring last year during training camp and was hampered throughout the first half of the season, missing two games.

McCoy stressed that his current injury is not nearly as bad as his hamstring injury from a year ago.

"It's not as bad, really it's not as bad at all, so that's a good thing," McCoy said.

If McCoy is unable to play, he likely will be replaced by backup Mike Gillislee. Gillislee had a 44-yard touchdown late in Buffalo's Week 6 win over the San Francisco 49ers. Buffalo also has veteran Reggie Bush and rookie Jonathan Williams at running back.

The Dolphins (2-4) have the 31st-ranked run defense in the NFL.

Defensive tackle Marcell Dareus (hamstring) and wide receiver Robert Woods (foot) are questionable. Woods has been wearing a boot on his injured right foot throughout the week. The Bills are already without top receiver Sammy Watkins (foot).

Tight end Charles Clay (ankle), fullback Jerome Felton (back), left tackle Cordy Glenn (ankle) and defensive tackle Kyle Williams (neck) are questionable.

Ryan said that first-round pick Shaq Lawson will play for the first time in his career. Lawson missed the first first six weeks of the season on the physically unable to perform list after undergoing offseason shoulder surgery.