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Italy has ended Spain's European Championship reign, beating the two-time defending champions 2-0 in the round of 16.

Giorgio Chiellini poked the ball into the net from close range in the 33rd minute after Spain goalkeeper David De Gea first parried Eder's free kick, then blocked Emanuele Giaccherini's follow up from the rebound.

Graziano Pelle added the second in injury time.

De Gea made four quality saves to keep his team in the game at Stade de France. In the first half, he denied Pelle and Giaccherini with diving saves to his left. De Gea blocked Eder's shot from a one-on-one chance in the 55th.

Italy goalkeeper Gianluigi Buffon preserved the lead in the 89th with a diving save low to his right to push away Gerard Pique's shot.

Italy will next play Germany in the quarterfinals on Saturday in Bordeaux.