They have donated more than $26 billion to their philanthropic foundation. They often team up with agencies that can provide diverse expertise, the Lasker foundation said, noting that they supported an international partnership that has helped immunize hundreds of millions of children against killer diseases. Their current priorities include polio, agriculture and family-planning information and services.
The Lasker clinical medical research award will be shared by Graeme Clark, an emeritus professor at the University of Melbourne in Australia, Ingeborg Hochmair of the company MED-EL in Innsbruck, Austria, and Blake Wilson of Duke University in North Carolina, for developing the modern cochlear (KAH'-klee-er) implant. More than 320,000 people around the world use the implants for severe hearing loss, the foundation said.
The devices stimulate the auditory nerve with electric signals. Hochmair and Clark worked independently, in the face of scientific skepticism that electrical stimulation could produce meaningful hearing. The implants were approved in the U.S. in 1985.
Wilson later designed a new way for implants to process speech, which has allowed most users to understand words and sentences with no visual cues. The advance fueled a growth in implant use that began in the early 1990s, the foundation said.
The Lasker award for basic medical research will be shared by Richard Scheller of the biotech company Genentech and Dr. Thomas Sudhof of Stanford University. With research they began independently in the late 1980s, they unraveled details of how brain cells release chemical messengers to communicate with each other. Scientists are beginning to find connections between the molecular equipment they studied and serious illnesses like Parkinson's disease, the foundation said.
Lasker Foundation: http://www.laskerfoundation.org