Food safety violations will be "severely punished," the food agency said on its website.
Starbucks Corp. on Tuesday said it removed from its shelves sandwiches made with chicken that originated at Husi. Burger King Corp. said it stopped using hamburger it received from a supplier that used product from Husi. Pizza restaurant chain Papa John's International Inc. announced it stopped using meat from Husi.
In Japan, McDonald's Corp. said it stopped selling McNuggets at more than 1,300 outlets that used chicken supplied by Husi. It said the Shanghai company had been supplying chicken to it since 2002.
A Shanghai broadcaster, Dragon TV, reported Sunday that Husi repackaged old beef and chicken and put new expiration dates on them. It said they were sold to McDonald's, KFC and Pizza Hut restaurants.
McDonald's and Yum Brands Inc., which owns KFC and Pizza Hut, said they immediately stopped using meat from Husi.
During a conference call to discuss its quarterly earnings Tuesday, McDonald's CEO Don Thompson said the company felt "a bit deceived" about the plant in question.
A third restaurant chain, Taiwanese-owned Dicos, also said Monday it stopped using meat from Husi.
In a statement, Husi said it was "appalled by the report" and would cooperate with the investigation. It promised to share the results with the public.
"Our company management believes this to be an isolated event, but takes full responsibility for the situation and will take appropriate actions swiftly and comprehensively," Husi said.
Some companies said they didn't deal with Husi but had discovered their suppliers bought meat from that company.
Food and drug safety is an unusually sensitive issue in China following scandals over the past decade in which infants, hospital patients and others have been killed or sickened by phony or adulterated milk powder, drugs and other goods.
Foreign fast food brands are seen as more reliable than Chinese competitors, though local brands have made big improvements in quality.
"If confirmed, the practices outlined in the report are completely unacceptable to McDonald's," the company's Chinese business said in a statement.
Yum's KFC is China's biggest restaurant chain, with more than 4,000 outlets and plans to open 700 more this year.
The company, based in Louisville, Kentucky, said in a statement that "food safety is the most important priority for us."