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Toronto • DeMar DeRozan matched a playoff high with 34 points, Kyle Lowry had 25 and the Toronto Raptors beat the Miami Heat 99-91 on Wednesday night to take a 3-2 lead in their Eastern Conference semifinal series.

Bismack Biyombo had 10 points for the Raptors, who can clinch their first conference finals berth with a win in Game 6 in Miami on Friday.

It was DeRozan's franchise-best 13th 20-point game in the playoffs and his sixth this postseason.

Dwyane Wade scored 20 for Miami, Goran Dragic and Josh Richardson each had 13 and Joe Johnson 11.

Toronto led by 20 in the first half and by 13 to start the fourth quarter before its lead shrunk to 88-87 when Wade made a pair of free throws with 1:54 left. DeRozan made a pair of free throws and, after a Miami turnover, Lowry made a long 3-pointer to put Toronto up 93-87 with 52 seconds left.

DeRozan sealed it by going 4 for 4 on his free throws in the final 21 seconds.

DeRozan jammed his sore right thumb while fouling Miami's Tyler Johnson with 8:19 remaining in the fourth. He headed to the locker room for treatment but returned four minutes later.

Lowry and DeRozan, who combined for 19 total points in Toronto's overtime loss in Game 4, scored 19 between them in the first quarter as the Raptors raced out to a 28-18 lead. Wade was the only Miami starter to make a field goal in the first as the Heat had more fouls (eight) than made baskets (six).

Biyombo had eight points in the second, electrifying the crowd by sandwiching a pair of dunks around a huge block on Wade. Toronto led 55-35 with 3:39 left but Dragic scored eight points as the Heat used a 10-0 run to cut the deficit to 55-45 at halftime.

Miami's Luol Deng left midway through the third with a sore left wrist and did not return. The Heat said X-rays were inconclusive. Deng scored four points and missed all eight of his field goal attempts.

Shortly after, Toronto's DeMarre Carroll injured his left wrist after being called for a charge, ending his night. Carroll went down in pain after the play before getting up and walking to the locker room while cradling his wrist. The Raptors said X-rays were negative.

Wade scored seven in the third but DeRozan had 11 as the Raptors took a 75-62 lead into the fourth.

Tip-ins

Heat • Coach Erik Spoelstra said C Hassan Whiteside continues to rest and receive therapy on his right knee. Spoelstra would not say whether Whiteside is any closer to returning. He was injured in the first half of Game 3 last Saturday. ... Amare Stoudemire started the game but Josh McRoberts replaced him to begin the third quarter.

Raptors • DeRozan also scored 34 in a Game 5 win over Indiana in the first round. ... All three of Toronto's second-quarter turnovers came during Miami's 10-0 run to end the half.