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New York • Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq stock market:

NYSE

• Merck & Co., down 36 cents to $50.05

The drug developer reported a drop in fourth-quarter profit and revenue.

• Chipotle Mexican Grill Inc., down $13.93 to $461.74

The fast-food chain reported continuing sales declines and said the scope of a federal criminal investigation has widened.

• Syngenta AG, up $1.66 to $80.23

Chinese state-owned chemical maker China National Chemical Corp. offered to buy the herbicide and pesticide giant for $43 billion.

• Lowe's Cos., down $4.45 to $67.42

The home improvement retailer is paying $2.3 billion to buy Rona and expand its footprint in Canada.

• General Motors Co., down 73 cents to $28.92

The automaker reported revenue that fell shy of Wall Street forecasts.

• Becton Dickinson and Co., down $3.97 to $141.08

The medical device maker reported revenue that fell short of forecasts.

Nasdaq

• IAC/InterActive Corp., down $5.09 to $45.78

The website operator's results fell short of Wall Street forecasts.

• Comcast Corp., up $3.25 to $57.84

The cable provider reported a boost in fourth-quarter profit and revenue.