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Tyus Jones scored 17 points and hit a clinching 3-pointer with about 10 seconds remaining Saturday night as No. 4 Duke ended No. 2 Virginia's 21-game home winning streak, 69-63.

Jones' 3-pointer was the fourth in the last four minutes for the Blue Devils (18-3, 5-3 Atlantic Coast Conference), who had missed 11 of 13 before hitting the long-range shots they needed.

Virginia (19-1, 7-1) started the second half with a 16-4 burst and led by 11 with under 11 minutes to play before some ill-advised shots, turnovers and Duke's shooting turned the tables.

Malcolm Brogdon led Virginia with 17 points and Justin Anderson had 11.

Quinn Cook, who scored 15, hit three 3-pointers in the last 4:38, including the one to give Duke the lead at 66-63 with 1:16 remaining. After Mike Tobey missed a free throw for Virginia, Tyus Jones hit the finisher with 9.9 seconds left, capping a game-ending 16-5 run for the Blue Devils.

Duke finished 28 for 55 (50.9 percent) and became the first team to shot above 50 percent against the Cavaliers this season.

No. 1 Kentucky 70, Alabama 55 • In Lexington, Kentucky, Karl-Anthony Towns scored all 12 of his points in the first half and Kentucky shot a season-best 59 percent to stay unbeaten.

Pittsburgh 76, No. 8 Notre Dame 72 • In Pittsburgh, James Robinson hit a runner with 12 seconds remaining to give Pittsburgh the lead for good in an upset victory over Notre Dame.

No. 10 Louisville 78, No. 13 North Carolina 68, OT • In Louisville, Kentucky, Terry Rozier scored Louisville's first six points in overtime and the Cardinals erased an 18-point second-half deficit to beat the Heels.

Rozier's sweeping layup 43 seconds into overtime gave Louisville (18-3, 6-2 Atlantic Coast Conference) a 62-60 lead. Two free throws following Kennedy Meeks' layup again put the Cardinals up and his 15-footer with 2:43 remaining gave Louisville the lead for good.

No. 5 Wisconsin 74, Iowa 63 • In Iowa City, Iowa, Frank Kaminsky had 24 points and nine rebounds to lead the Badgers.

No. 7 Villanova 68, DePaul 55 • In Rosemont, Illinois, Ryan Arcidiacono scored all 18 of his points in the second half and Villanova beat DePaul to take the Big East lead.

No. 9 Kansas 68, Kansas State 57 • In Lawrence, Kansas, Perry Ellis had 16 points and 12 rebounds and Kansas bolted to a big lead.

No. 18 Northern Iowa 70, No. 12 Wichita State 54 • In Cedar Falls, Iowa, Seth Tuttle scored a career-high 29 points and the Panthers ended the Shockers' Missouri Valley Conference regular-season winning streak at 27 games.

Richmond 64, No. 14 VCU 55 • In Richmond, Virginia, Kendall Anthony scored 20 of his 22 points in the second half during the Spiders' comeback victory over the Rams.

No. 15 Iowa State 83, TCU 66 • In Ames, Iowa, Georges Niang scored 23 points and Monte Morris and Bryce Dejean-Jones each added 16 for the Cyclones.

No. 17 West Virginia 77, Texas Tech 58 • In Morgantown, West Virginia, Devin Williams scored 18 points and the Mountaineers forced 26 turnovers.

No. 20 Baylor 83, No. 19 Texas 60 • In Waco, Texas, Kenny Chery scored 19 of his 23 points in the second half and Royce O'Neale added 20 points to lift the Bears over the Longhorns.

No. 21 Georgetown 67, Creighton 40 • At Omaha, Nebraska, D'Vauntes Smith-Rivera scored 24 points and the Hoyas held Blue Jays without a field goal for more than 17 minutes.

No. 22 Indiana 72, Rutgers 64 • In Bloomington, Indiana, James Blackmon Jr. scored 20 points and Nick Zeisloft made two 3-pointers in a late 8-0 run in the Hoosiers' victory.

No. 24 Oklahoma 64, Oklahoma State 56 • In Stillwater, Oklahoma, Jordan Woodard scored a season-high 17 points for the Sooners.

No. 25 Butler 72, Marquette 68, OT • In Milwaukee, Andrew Chrabascz scored 30 points, the Bulldogs overcame a 10-point deficit in the final 4:21 of regulation. —

Top 25 scores

• No. 1 Kentucky 70, Alabama 55 • No. 4 Duke 69, No. 2 Virginia 63, • No. 3 Gonzaga vs. Memphis, late • No. 5 Wisconsin 74, Iowa 63 • No. 7 Villanova 68, DePaul 55 • Pittsburgh 76, No. 8 Notre Dame 72 • No. 9 Kansas 68, Kansas State 57 • No. 10 Louisville 78, No. 13 North Carolina 68 • No. 18 Northern Iowa 70, No. 12 Wichita State 54 • Richmond 64, No. 14 VCU 55 • No. 15 Iowa State 83, TCU 66 • No. 17 West Virginia 77, Texas Tech 58 • No. 20 Baylor 83, No. 19 Texas 60

• No. 21 Georgetown 67, Creighton 40 • No. 22 Indiana 72, Rutgers 64 • No. 25 Butler 72, Marquette 68